We show that virtual particles, despite being unobservable, can be described by quantum operators which can be interpreted under certain conditions as valid qubit quantum states. For a single virtual fermion, we prove that such a state is a separable mixed 2-qubit state with a well-defined finite temperature. For spin-1 virtual bosons, we find them to be associated to 4-qubit operators which can be interpreted as quantum states for some gauges. We also study the creation of virtual pairs of fermions, where the pair is shown to be associated to an entangled 4-qubit operator, and show the corresponding quantum circuit. Finally, we prove that renormalization does not structurally affect these results. These findings represent new connections between quantum field theory, quantum information and quantum thermodynamics.