Implantable optoelectronic and electronic devices, such as organic light-emitting diodes (OLEDs) and organic thin-film transistors, have revolutionized medical diagnostics and therapeutics. Those devices enable precise monitoring, stimulation, and treatment of biological tissues with high spatial and temporal resolution.[1-2] Currently, the focus in this field is the development of transient or bioresorbable devices, designed to fully dissolve, disintegrate, or vanish at controlled rates or in response to specific triggers such as temperature, pH levels, or enzymatic activity.
In this study, we explored the potential of various substrates, namely poly (lactic-co-glycolic) acid (PLGA), DegraPol®, Konjac and chitosan, as biocompatible, lightweight, and mechanically flexible materials for the fabrication of OLEDs. The results demonstrated that chitosan-based OLEDs can completely disintegrate when immersed in a lysozyme solution (a hydrolytic enzyme present in the human body).[3]
The successful degradation of the device suggests a promising route toward the development of transient optoelectronic implants that can safely dissolve in the body after fulfilling their medical function. From an environmental perspective, the use of chitosan-based electronic devices contributes to the reduction of electronic waste, aligning with global efforts to promote eco-friendly and sustainable technologies. Overall, our findings underscore the relevance of chitosan-based OLEDs for future implantable biomedical devices that are both patient-safe and environmentally responsible.